Endocrine Abstracts

Aim: Antithyroid drugs (ATD) methimazole and propylthiouracil (PTU) are the drugs of choice for treatment of hyperthyroidism. Agranulocytosisis, the most severe side effect of these medications, occurs in 0.2–0.5% of patients. ATDs are used also in patients with amiodarone-induced thyrotoxicosis (AIT). Our objective was to evaluate the risk for agranulocytosis, associated with ATDs, in patients with AIT, and to compare the risk with the risk of ATD-associated agranulocyto...

Background: The association between primary hyperparathyroidism (PHPT) and cardiovascular disease (CVD) morbidity and mortality is well known in symptomatic PHPT patients. Atherosclerosis is considered nowadays as an inflammatory process. Elevated serum levels of acute phase proteins, C-reactive protein (CRP) and the proinflammatory cytokines tumor necrosis factor alpha (TNF α), Interleukin-6 (IL-6), as well as insulin resistance, indicating chronic subclinical inflammati...